PD Dr. Matthias Woenckhaus

Chefarzt Institut für Pathologie

Stellvertr. Leiter Onkologisches Zentrum

07931 58-2801 07931 58-2890 pthlgcrtsbbtgrppd

Lebenslauf

1986 - 1993	Studium der Humanmedizin an der Albert-Ludwigs Universität Freiburg, Medizinisches Staatsexamen 1993
1993	Promotion bei Prof. Dr. K. G. Petersen, Innere Medizin, Freiburg (Dissertationsthema: „Verhalten der Vasomotion unter Narkose beim Menschen“)
1993 - 1994	Arzt im Praktikum an der II.Medizinischen Klinik des Städtischen Krankenhauses Kemperhof, Koblenz
1994 - 1998	Assistenzarzt am Pathologischen Institut der Fakultät für Klinische Medizin der Universität Heidelberg in Mannheim (Prof. Dr. U. Bleyl)
1998	Eintritt als Assistenzarzt in das Institut für Pathologie der Universität Regensburg (Prof. Dr. F. Hofstädter)
2001	Anerkennung als Facharzt für Pathologie (Bayerische Landesärztekammer), Ernennung zum Oberarzt
2007	Erwerb der Habilitation (Thema: „Gewebliche und molekulare Schädigungsmuster in Lungenkarzinomen und im Lungengewebe von Rauchern“)
2008	Lehrbefugnis für das Fach Pathologie an der Universität Regensburg
02/2008	Mitarbeit im Pathologischen Institut Koblenz
Seit 11/2008	Chefarzt für Pathologie im Caritas-Krankenhaus Bad Mergentheim

Veröffentlichungen

Littoral cell angioma of the spleen.
Cui XW, Ignee A, De Molo C, Schreiber-Dietrich D, Woenckhaus M, Dietrich CF.
Z Gastroenterol. 2013 Feb;51(2):209-12. doi: 10.1055/s-0032-1325556. Epub 2013 Feb 15. Review.
Expression of the MAP kinase phosphatase DUSP4 is associated with microsatellite instability in colorectal cancer (CRC) and causes increased cell proliferation.
Gröschl B, Bettstetter M, Giedl C, Woenckhaus M, Edmonston T, Hofstädter F, Dietmaier W.
Int J Cancer. 2013 Apr 1;132(7):1537-46. doi: 10.1002/ijc.27834. Epub 2012 Nov 23.
Papillary renal cell carcinoma in the transplanted kidney - a case report focusing on contrast enhanced ultrasound features.
Ignee A, Hocke M, Selbach J, Cui XW, Woenckhaus M, Dietrich CF.
Med Ultrason. 2012 Sep;14(3):246-50.
Uncommon lesions in the internal auditory canal (IAC): review of the literature and case report.
Rohlfs AK, Burger R, Viebahn C, Held P, Woenckhaus M, Römer FW, Strutz J.
J Neurol Surg A Cent Eur Neurosurg. 2012 May;73(3):160-6. doi: 10.1055/s-0032-1304211. Epub 2012 Apr 30.
Imaging of gastrointestinal stromal tumours with modern ultrasound techniques - a pictorial essay.
Dietrich CF, Jenssen C, Hocke M, Cui XW, Woenckhaus M, Ignee A.
Z Gastroenterol. 2012 May;50(5):457-67. doi: 10.1055/s-0031-1282076. Epub 2012 May 11. Review.
Biliary papillomatosis and new ultrasound imaging modalities.
Cui XW, Ignee A, Braden B, Woenckhaus M, Dietrich CF.
Z Gastroenterol. 2012 Feb;50(2):226-31. doi: 10.1055/s-0031-1281967. Epub 2012 Feb 1. Review.
Contrast-enhanced ultrasound in diagnosing liver malignancy.
Zuber-Jerger I, Schacherer D, Woenckhaus M, Jung EM, Schölmerich J, Klebl F.
Clin Hemorheol Microcirc. 2009;43(1-2):109-18. doi: 10.3233/CH-2009-1225.
Exploration of the APC/beta-catenin (WNT) pathway and a histologic classification system for pulmonary artery intimal sarcoma. A study of 18 cases.
Gaumann A, Bode-Lesniewska B, Zimmermann DR, Fanburg-Smith JC, Kirkpatrick CJ, Hofstädter F, Woenckhaus M, Stoehr R, Obermann EC, Dietmaier W, Hartmann A.
Virchows Arch. 2008 Nov;453(5):473-84. doi: 10.1007/s00428-008-0671-0. Epub 2008 Sep 20.
Fatal Pneumocystis pneumonia following rituximab administration for rheumatoid arthritis.
Teichmann LL, Woenckhaus M, Vogel C, Salzberger B, Schölmerich J, Fleck M.
Rheumatology (Oxford). 2008 Aug;47(8):1256-7. doi: 10.1093/rheumatology/ken234. Epub 2008 Jun 21. No abstract available.
Prognostic value of FHIT, CTNNB1, and MUC1 expression in non-small cell lung cancer.
Woenckhaus M, Merk J, Stoehr R, Schaeper F, Gaumann A, Wiebe K, Hartmann A, Hofstaedter F, Dietmaier W.
Hum Pathol. 2008 Jan;39(1):126-36. Epub 2007 Oct 18.
A patient with testicular pseudolymphoma - a rare condition mimicking malignancy: a case report.
Ganzer R, Burger M, Woenckhaus M, Wieland WF, Blana A.
J Med Case Rep. 2007 Aug 25;1:71.
Effectiveness of parathyroid-hormone measurement in detecting patients with multiple gland disease causing primary hyperparathyroidism.
Agha A, Scherer MN, Mantouvalou K, Woenckhaus M, Froehlich D, Barlage S, Dada A, Schlitt HJ.
Langenbecks Arch Surg. 2007 Nov;392(6):703-8. Epub 2007 May 26.
Frequent loss of SFRP1 expression in multiple human solid tumours: association with aberrant promoter methylation in renal cell carcinoma.
Dahl E, Wiesmann F, Woenckhaus M, Stoehr R, Wild PJ, Veeck J, Knüchel R, Klopocki E, Sauter G, Simon R, Wieland WF, Walter B, Denzinger S, Hartmann A, Hammerschmied CG.
Oncogene. 2007 Aug 16;26(38):5680-91. Epub 2007 Mar 12.
Renal cell carcinoma metastases to the thyroid gland-8 cases reported.
Iesalnieks I, Trupka A, Raab M, Glockzin G, Woenckhaus M, Schlitt HJ, Agha A.
Thyroid. 2007 Jan;17(1):49-52.
Insular carcinomas of the thyroid exhibit poor prognosis and long-term survival in comparison to follicular and papillary T4 carcinomas.
Agha A, Glockzin G, Woenckhaus M, Dietmaier W, Iesalnieks I, Schlitt HJ.
Langenbecks Arch Surg. 2007 Nov;392(6):671-7. Epub 2007 Jan 10.
Fatty liver: imaging patterns and pitfalls.
Hamer OW, Aguirre DA, Casola G, Lavine JE, Woenckhaus M, Sirlin CB.
Radiographics. 2006 Nov-Dec;26(6):1637-53. Review.
Smoking and cancer-related gene expression in bronchial epithelium and non-small-cell lung cancers.
Woenckhaus M, Klein-Hitpass L, Grepmeier U, Merk J, Pfeifer M, Wild P, Bettstetter M, Wuensch P, Blaszyk H, Hartmann A, Hofstaedter F, Dietmaier W.
J Pathol. 2006 Oct;210(2):192-204.
Renal cell carcinoma metastases to the thyroid gland -- report of 3 cases and review of the literature
Iesalnieks I, Woenckhaus M, Glockzin G, Schlitt HJ, Agha A.
Zentralbl Chir. 2006 Jun;131(3):235-9. German.
Defining high-fat-diet rat models: metabolic and molecular effects of different fat types.
Buettner R, Parhofer KG, Woenckhaus M, Wrede CE, Kunz-Schughart LA, Schölmerich J, Bollheimer LC.
J Mol Endocrinol. 2006 Jun;36(3):485-501.
Nuclear and cytoplasmic Maspin expression in primary non-small cell lung cancer.
Woenckhaus M, Bubendorf L, Dalquen P, Foerster J, Blaszyk H, Mirlacher M, Soler M, Dietmaier W, Sauter G, Hartmann A, Wild PJ.
J Clin Pathol. 2007 May;60(5):483-6. Epub 2006 May 12.
Tissue microarray analysis of methylthioadenosine phosphorylase protein expression in melanocytic skin tumors.
Wild PJ, Meyer S, Bataille F, Woenckhaus M, Ameres M, Vogt T, Landthaler M, Pauer A, Klinkhammer-Schalke M, Hofstaedter F, Bosserhoff AK.
Arch Dermatol. 2006 Apr;142(4):471-6.
Nuclear Maspin expression is associated with response to adjuvant 5-fluorouracil based chemotherapy in patients with stage III colon cancer.
Dietmaier W, Bettstetter M, Wild PJ, Woenckhaus M, Rümmele P, Hartmann A, Dechant S, Blaszyk H, Pauer A, Klinkhammer-Schalke M, Hofstädter F.
Int J Cancer. 2006 May 1;118(9):2247-54.
Microsatellite analysis of pleural supernatants could increase sensitivity of pleural fluid cytology.
Woenckhaus M, Grepmeier U, Werner B, Schulz C, Rockmann F, Wild PJ, Röckelein G, Blaszyk H, Schuierer M, Hofstaedter F, Hartmann A, Dietmaier W.
J Mol Diagn. 2005 Oct;7(4):517-24.
Deletions at chromosome 2q and 12p are early and frequent molecular alterations in bronchial epithelium and NSCLC of long-term smokers.
Grepmeier U, Dietmaier W, Merk J, Wild PJ, Obermann EC, Pfeifer M, Hofstaedter F, Hartmann A, Woenckhaus M.
Int J Oncol. 2005 Aug;27(2):481-8.
Multitarget FISH and LOH analyses at chromosome 3p in non-small cell lung cancer and adjacent bronchial epithelium.
Woenckhaus M, Grepmeier U, Wild PJ, Merk J, Pfeifer M, Woenckhaus U, Stoelcker B, Blaszyk H, Hofstaedter F, Dietmaier W, Hartmann A.
Am J Clin Pathol. 2005 May;123(5):752-61.
Efficient analysis of hepatic glucose output and insulin action using a liver slice culture system.
Buettner R, Straub RH, Ottinger I, Woenckhaus M, Schölmerich J, Bollheimer LC.
Horm Metab Res. 2005 Mar;37(3):127-32.
Elevated nuclear maspin expression is associated with microsatellite instability and high tumour grade in colorectal cancer.
Bettstetter M, Woenckhaus M, Wild PJ, Rümmele P, Blaszyk H, Hartmann A, Hofstädter F, Dietmaier W.
J Pathol. 2005 Apr;205(5):606-14.
Quantitative gene expression analysis of fractalkine using laser microdissection in biopsies from kidney allografts with acute rejection.
Pietrzyk MC, Banas B, Wolf K, Rümmele P, Woenckhaus M, Hoffmann U, Krämer BK, Fischereder M.
Transplant Proc. 2004 Nov;36(9):2659-61.
Association of Crohn's disease and latent celiac disease: a case report and review of the literature.
Schedel J, Rockmann F, Bongartz T, Woenckhaus M, Schölmerich J, Kullmann F.
Int J Colorectal Dis. 2005 Jul;20(4):376-80. Epub 2004 Dec 1. Review.
Autoimmune cholangitis with vasculitic ulcers, rheumatoid arthritis and IgA glomerulonephritis
Schedel J, Mayer S, Woenckhaus M, Kiss E, Schölmerich J, Rogler G.
Dtsch Med Wochenschr. 2004 Nov 5;129(45):2409-12. German.
Discrepancy between mRNA and protein expression of tumour suppressor maspin in synovial tissue may contribute to synovial hyperplasia in rheumatoid arthritis.
Schedel J, Distler O, Woenckhaus M, Gay RE, Simmen B, Michel BA, Müller-Ladner U, Gay S.
Ann Rheum Dis. 2004 Oct;63(10):1205-11.
A patient with myelofibrosis complicated by refractory ascites and portal hypertension: to tips or not to tips? A case report with discussion of the mechanism of ascites formation.
Wiest R, Strauch U, Wagner H, Strotzer M, Woenckhaus M, Schröder G, Schölmerich J, Lock G.
Scand J Gastroenterol. 2004 Apr;39(4):389-94.
Unilateral adult malignant optic nerve glioma.
Wabbels B, Demmler A, Seitz J, Woenckhaus M, Bloss HG, Lorenz B.
Graefes Arch Clin Exp Ophthalmol. 2004 Sep;242(9):741-8. Review.
Vertigo and hearing disturbance as the first sign of a glioblastoma (World Health Organization grade IV).
Licht AK, Schulmeyer F, Allert M, Held P, Woenckhaus M, Strutz J.
Otol Neurotol. 2004 Mar;25(2):174-7.
"Tingling feet," forgetfulness, and progressive personality changes in a 63-year-old patient.
Karrasch T, Weil M, Voltz R, Schulz C, Audebert F, Woenckhaus M, Hofstädter F, Bogdahn U, Schölmerich J, Schäffler A, Steinbrecher A.
Internist (Berl). 2004 Mar;45(3):341-6. German.
Microsatellite instability at chromosome 8p in non-small cell lung cancer is associated with lymph node metastasis and squamous differentiation.
Woenckhaus M, Stoehr R, Dietmaier W, Wild PJ, Zieglmeier U, Foerster J, Merk J, Blaszyk H, Pfeifer M, Hofstaedter F, Hartmann A.
Int J Oncol. 2003 Nov;23(5):1357-63.
WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer.
Wissmann C, Wild PJ, Kaiser S, Roepcke S, Stoehr R, Woenckhaus M, Kristiansen G, Hsieh JC, Hofstaedter F, Hartmann A, Knuechel R, Rosenthal A, Pilarsky C.
J Pathol. 2003 Oct;201(2):204-12.
Langerhans' cell histiocytosis with bilateral temporal bone involvement.
Kleinjung T, Woenckhaus M, Bachthaler M, Wolff JE, Wolf SR.
Am J Otolaryngol. 2003 Jul-Aug;24(4):265-70.
Induction of apoptosis before shedding of human intestinal epithelial cells
Grossmann J, Walther K, Artinger M, Rümmele P, Woenckhaus M, Schölmerich J.
Am J Gastroenterol. 2002 Jun;97(6):1421-8.
Massive steatosis hepatis: an unusual manifestation of Whipple's disease.
Schultz M, Hartmann A, Dietmaier W, Woenckhaus M, Lock G.
Am J Gastroenterol. 2002 Mar;97(3):771-2.
Correlation between neovascularisation and neuroendocrine differentiation in prostatic carcinoma.
Grobholz R, Bohrer MH, Siegsmund M, Jünemann KP, Bleyl U, Woenckhaus M.
Pathol Res Pract. 2000;196(5):277-84.
A rare fatal course of disease in a patient with spontaneous pituitary apoplexy. Case report and literature review.
Lange M, Woenckhaus M, Segiet W, Oeckler R.
Neurosurg Rev. 1999 Oct;22(2-3):163-9.
Cavernous hemangioma of the rectum--a rare cause of peranal hemorrhage.
Freudenberg S, Lorenz D, Manegold BC, Woenckhaus M.
Chirurg. 1998 Jul;69(7):780-2. German.

PD Dr. Matthias Woenckhaus

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